Author Pukrop, Tobias

• 2022 | Journal Article | Research Paper | 
  ​ ​High-Throughput Profiling of Colorectal Cancer Liver Metastases Reveals Intra- and Inter-Patient Heterogeneity in the EGFR and WNT Pathways Associated with Clinical Outcome​
  Menck, K.; Wlochowitz, D.; Wachter, A.; Conradi, L.-C.; Wolff, A.; Scheel, A. H. & Korf, U. et al.​ (2022) 
  Cancers, 14(9).​ DOI: https://doi.org/10.3390/cancers14092084 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​WNT11/ROR2 signaling is associated with tumor invasion and poor survival in breast cancer​
  Menck, K.; Heinrichs, S.; Wlochowitz, D.; Sitte, M.; Noeding, H.; Janshoff, A. & Treiber, H. et al.​ (2021) 
  Journal of Experimental & Clinical Cancer Research, 40(1) art. 395​.​ DOI: https://doi.org/10.1186/s13046-021-02187-z 
  ​Details  DOI 

• 2020 | Journal Article
  ​ ​5-Aminolevulinic Acid Fluorescence Indicates Perilesional Brain Infiltration in Brain Metastases​
  Schatlo, B.; Stockhammer, F.; Barrantes-Freer, A.; Bleckmann, A.; Siam, L.; Pukrop, T. & Rohde, V.​ (2020) 
  World Neurosurgery: X, 5 pp. 100069​.​ DOI: https://doi.org/10.1016/j.wnsx.2019.100069 
  ​Details  DOI 

• 2020 | Journal Article | 
  ​ ​LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer​
  Blazquez, R.; Rietkötter, E.; Wenske, B.; Wlochowitz, D.; Sparrer, D.; Vollmer, E. & Müller, G. et al.​ (2020) 
  International Journal of Cancer, 146(11) pp. 3170​-3183​.​ DOI: https://doi.org/10.1002/ijc.32742 
  ​Details  DOI  PMID  PMC 

• 2018 | Journal Article
  ​ ​Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFRmut NSCLC in diagnosis, follow-up and treatment​
  Lüke, F.; Blazquez, R.; Yamaci, R. F.; Lu, X.; Pregler, B.; Hannus, S. & Menhart, K. et al.​ (2018) 
  Oncotarget, 9(27) pp. 18844-18857​.​ DOI: https://doi.org/10.18632/oncotarget.24787 
  ​Details  DOI  PMID  PMC 

• 2018 | Journal Article
  ​ ​PI3K: A master regulator of brain metastasis-promoting macrophages/microglia​
  Blazquez, R.; Wlochowitz, D.; Wolff, A.; Seitz, S.; Wachter, A.; Perera-Bel, J. & Bleckmann, A. et al.​ (2018) 
  Glia, 66(11) pp. 2438​-2455​.​ DOI: https://doi.org/10.1002/glia.23485 
  ​Details  DOI  PMID  PMC 

• 2017 | Journal Article | 
  ​ ​LEF1 reduces tumor progression and induces myodifferentiation in a subset of rhabdomyosarcoma​
  Draeger, J.; Simon-Keller, K.; Pukrop, T.; Klemm, F.; Wilting, J.; Sticht, C. & Dittmann, K. et al.​ (2017) 
  Oncotarget, 8(2) pp. 3259​-3273​.​ DOI: https://doi.org/10.18632/oncotarget.13887 
  ​Details  DOI  PMID  PMC  WoS 

• 2017 | Journal Article
  ​ ​PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression​
  Hohensee, I.; Chuang, H.-N.; Grottke, A.; Werner, S.; Schulte, A.; Horn, S. & Lamszus, K. et al.​ (2017) 
  Oncotarget, 8(4) pp. 6155​-6168​.​ DOI: https://doi.org/10.18632/oncotarget.14047 
  ​Details  DOI  PMID  PMC  WoS 

• 2016 | Conference Abstract
  ​ ​DVL3 in breast cancer and tumor progression​
  Schubert, A.; Bleckmann, A.; Pukrop, T. & Binder, C.​ (2016)
  Oncology Research and Treatment, 39 
  Basel​: Karger.
  ​Details  WoS 

• 2016 | Journal Article
  ​ ​The anthelmintic niclosamide inhibits colorectal cancer cell lines via modulation of the canonical and noncanonical Wnt signaling pathway​
  Monin, M. B.; Krause, P.; Stelling, R.; Bocuk, D.; Niebert, S.; Klemm, F. & Pukrop, T. et al.​ (2016) 
  Journal of Surgical Research, 203(1) pp. 193​-205​.​ DOI: https://doi.org/10.1016/j.jss.2016.03.051 
  ​Details  DOI  PMID  PMC  WoS 

• 2015 | Journal Article | 
  ​ ​Anti-CSF-1 treatment is effective to prevent carcinoma invasion induced by monocyte-derived cells but scarcely by microglia.​
  Rietkötter, E.; Bleckmann, A.; Bayerlová, M.; Menck, K.; Chuang, H.-N.; Wenske, B. & Schwartz, H. et al.​ (2015) 
  Oncotarget, 6(17) pp. 15482​-15493​.​ DOI: https://doi.org/10.18632/oncotarget.3855 
  ​Details  DOI  PMID  PMC 

• 2015 | Conference Abstract
  ​ ​The crucial impact of the unique organ-specific defense system during colonization and outgrowth of brain metastasis​
  Pukrop, T. & Hanisch, U.-K.​ (2015)
  Clinical & Experimental Metastasis, 32(3) 
  Dordrecht​: Springer.
  ​Details  WoS 

• 2015 | Conference Abstract
  ​ ​Wnt5a signaling mediates cell migration and invasion of Hodgkin Lymphoma in vitro and in xenograft models​
  Linke, F.; Zaunig, S.; von Bonin, F.; Wilting, J.; Bryja, V.; Pukrop, T. & Truemper, L. H. et al.​ (2015)
  Oncology Research and Treatment, 38 
  Basel​: Karger.
  ​Details  WoS 

• 2015 | Journal Article
  ​ ​Tyrphostin AG126 Exerts Neuroprotection in CNS Inflammation by a Dual Mechanism​
  Menzfeld, C.; John, M.; van Rossum, D.; Regen, T.; Scheffel, J.; Janova, H.   & Goetz, A. A. et al.​ (2015) 
  Glia, 63(6) pp. 1083​-1099​.​ DOI: https://doi.org/10.1002/glia.22803 
  ​Details  DOI  PMID  PMC  WoS 

• 2015 | Journal Article | 
  ​ ​The metastatic infiltration at the metastasis/brain parenchyma-interface is very heterogeneous and has a significant impact on survival in a prospective study​
  Siam, L.; Bleckmann, A.; Chaung, H.-N.; Mohr, A.; Klemm, F.; Barrantes-Freer, A. & Blazquez, R. et al.​ (2015) 
  Oncotarget, 6(30) pp. 29254​-29267​.​ DOI: https://doi.org/10.18632/oncotarget.4201 
  ​Details  DOI  PMID  PMC  WoS 

• 2015 | Journal Article | 
  ​ ​Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN​
  Menck, K.; Scharf, C.; Bleckmann, A.; Dyck, L.; Rost, U.; Wenzel, D. & Dhople, V. M. et al.​ (2015) 
  Journal of Molecular Cell Biology, 7(2) pp. 143​-153​.​ DOI: https://doi.org/10.1093/jmcb/mju047 
  ​Details  DOI  PMID  PMC  WoS 

• 2014 | Conference Abstract
  ​ ​Impact of pre-OP frailty on mortality after resection of limited brain metastases​
  Bleckmann, A.; Kirchner, B.; Siam, L. & Pukrop, T.​ (2014)
  Oncology Research and Treatment, 37 pp. 118​-119. 
  Basel​: Karger.
  ​Details  WoS 

• 2014 | Conference Abstract
  ​ ​EMMPRIN/CD147-positive tumor cell microvesicles are pro-invasive and detectable in the blood of cancer patients with metastasis​
  Menck, K.; Bleckmann, A.; Scharf, C.; Pukrop, T.; Dyck, L.; Klemm, F. & Binder, C.​ (2014)
  Oncology Research and Treatment, 37 pp. 285​-286. 
  Basel​: Karger.
  ​Details  WoS 

• 2014 | Journal Article | 
  ​ ​Depletion of Cutaneous Macrophages and Dendritic Cells Promotes Growth of Basal Cell Carcinoma in Mice​
  Koenig, S.; Nitzki, F.; Uhmann, A.; Dittmann, K.; Theiss-Suennemann, J.; Herrmann, M. & Reichardt, H. M. et al.​ (2014) 
  PLoS ONE, 9(4) art. e93555​.​ DOI: https://doi.org/10.1371/journal.pone.0093555 
  ​Details  DOI  PMID  PMC  WoS 

• 2014 | Journal Article
  ​ ​Isolation of Human Monocytes by Double Gradient Centrifugation and Their Differentiation to Macrophages in Teflon-coated Cell Culture Bags​
  Menck, K.; Behme, D.; Pantke, M.; Reiling, N.; Binder, C.; Pukrop, T. & Klemm, F.​ (2014) 
  Journal of Visualized Experiments,(91) art. e51554​.​ DOI: https://doi.org/10.3791/51554 
  ​Details  DOI  PMID  PMC  WoS 

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